Chloroquine: Consideration of Maximum Daily Dose (3.5 mg/kg Ideal Body Weight) Prevents Retinopathy

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Chloroquine retinopathy: is there a safe daily dose?

Published case reports of chloroquine retinopathy rarely include details of daily dosage, but 30 reports where this information was available included 78 patients who developed impaired visual acuity an 13 had received daily doses of 250 mg or less. Eleven cases of ocular toxicity attributed to chloroquine were reported to the Committee on Safety of Medicines but only 2 developed impaired visio...

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[Chloroquine retinopathy].

Chloroquine Retinopathy refers to the changes seen in the retina of patients due to long term use of chloroquine. The late presentation, classically described as bull’s eye maculopathy, is preceded by a number of subtle changes. With the advent of new investigation modalities and regular screening, it is possible to prevent irreversible retinal damage due to this important and widely used drug....

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Chloroquine Retinopathy Ideal body weight Dr. F.R. Ochsendorf, Department of Dermatology, University Hospital, Theodor-Stern-Kai 7, D-60590 Frankfurt/M. (Germany) In this journal, Lipsker et al. [1] emphasized the efficacy of the combination of chloroquine and quinacrine for the treatment of resistant cutaneous lupus erythematosus. 20% of their patients (3/15), however, developed abnormalities ...

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ژورنال

عنوان ژورنال: Dermatology

سال: 1996

ISSN: 1018-8665,1421-9832

DOI: 10.1159/000246421